Brain Phenotype of Transgenic Mice Overexpressing Cystathionine β-Synthase
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چکیده
منابع مشابه
Brain Phenotype of Transgenic Mice Overexpressing Cystathionine β-Synthase
BACKGROUND The cystathionine β-synthase (CBS) gene, located on human chromosome 21q22.3, is a good candidate for playing a role in the Down Syndrome (DS) cognitive profile: it is overexpressed in the brain of individuals with DS, and it encodes a key enzyme of sulfur-containing amino acid (SAA) metabolism, a pathway important for several brain physiological processes. METHODOLOGY/PRINCIPAL FI...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0029056